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Question of the Day

The transdermal fentanyl patch is more often prescribed for baseline pain rather than breakthrough pain. Why?

The fentanyl transdermal patch has a slow onset and long duration of action. Therapeutic blood levels are achieved 12-16 hours after application of a patch and the half-life is 16-22 hours after removal of the patch. A fentanyl patch, therefore, would not effectively treat breakthrough pain.